Non‐immune hydrops fetalis: A short review of etiology and pathophysiology
Identifieur interne : 004720 ( Main/Exploration ); précédent : 004719; suivant : 004721Non‐immune hydrops fetalis: A short review of etiology and pathophysiology
Auteurs : Carlo Bellini [Italie] ; Raoul Cm Hennekam [Pays-Bas]Source :
- American Journal of Medical Genetics Part A [ 1552-4825 ] ; 2012-03.
Abstract
Hydrops fetalis is an excessive accumulation of fetal fluid. Hydrops is traditionally classified into either immune or non‐immune hydrops (NIHF), but in practice, nowadays in the Western world >90% of hydrops is of non‐immune origin. The basis of the disorder is an imbalance in the regulation of fetal fluid movement between the vascular and interstitial space. We previously suggested a diagnostic flow‐chart for NIHF. In this short review we describe the main mechanisms leading to NIHF. © 2012 Wiley Periodicals, Inc.
Url:
DOI: 10.1002/ajmg.a.34438
Affiliations:
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<front><div type="abstract" xml:lang="en">Hydrops fetalis is an excessive accumulation of fetal fluid. Hydrops is traditionally classified into either immune or non‐immune hydrops (NIHF), but in practice, nowadays in the Western world >90% of hydrops is of non‐immune origin. The basis of the disorder is an imbalance in the regulation of fetal fluid movement between the vascular and interstitial space. We previously suggested a diagnostic flow‐chart for NIHF. In this short review we describe the main mechanisms leading to NIHF. © 2012 Wiley Periodicals, Inc.</div>
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